Animal experimentation and my empathy
I also posted this topic in another forum some time ago, but the topic got closed after a while because this is an emotional topic after all and some people get a little upset, I hope we can discuss this topic in a mature way because I would not like it if this topic also get closed!
Anyway, lets start......
I could never be a scientist myself because I could never do these tests on animals because of my empathy for them, but my husband is a scientist and he has no problem with it in the name of science.
My husband is very well informed about animal experimentation and different levels of its use in contemporary science. He is also aware of the regulations of the ethics committees that take part in granting scientists permissions for use of laboratory animals in research.
One of the most common examples is the use of animals for testing of new pharmaceuticals before they enter extensive testing on humans in clinical trials. As I was told, animals provide a genetically stable and controlled background for vaccination experiments (there are specific breeds of animals with a very well defined genetic background such as the well known BALB/c mice, nude mice (no immune system), Wistar rats etc. which have been produced through controlled breeding through many generations).
Another technique very commonly applied is production of monoclonal antibodies to human proteins or other types of antigens which are normally coupled to "keyhole limpet hemocyanine" (KLH) and this together with an adjuvant for the innate immune system (like Freud´s incomplete adjuvant) is injected in mice or rats and over the course of several weeks, the animals are put under anesthesia, their spleen removed, and they are then humanely euthanized by a inter-cardiac pentobarbital injection together with lidocaine followed by mechanical cervical dislocation or decapitation. The antibodies produced by the B-cells in the spleen are then immortalized through fusion with mouse myeloma cells and are then screened against the antigen in several immunological assays to find the best clones which produce the desired antibody.
He also told me that there are certain things for which the use of animals (or at least organisms other than human) is absolutely unavoidable, but there are cases where humans could be used more (like for pharmaceutical testing trials) but are not because of several important practical as well as some ethical issues. These were just a few examples that he told me about.
- And now comes my dilemma. He told me that there are very strict animal welfare committees which grant or denie permission to scientists to work with animals. In a way I am okay with it, but at the same time I'm not okay with it.
Because I fell sorry for all those little animals who are used for human purposes without it being their choice. What do you think? Do you think that the end justifies the means or do you think there are some other points to this that neither the scientists or the animal welfare personnel have thought about?
Last edited by Marian; 06-25-2012 at 02:01 AM.
Mistook the nods.
I like not having polio or any number of other diseases. I like not going blind from the shampoo I use. I like people (especially women) to not have their faces melted off when they wear make-up.
If 100,000 monkeys or rabbits or mice die to save one human life, it's worth it. One human life is worth more than 100,000 lesser-animal lives. I am absolutely for animal testing, if it protects a single human life.
NOTE: I'll reply to this with a more in-depth response when I'm a a bit more sober. Excellent thread idea, I love it!
Close my eyes just to look at you.
I am all for the fair treatment of animals. I always ensure that the cosmetics and perfumes I buy are not tested on animals. It is unfortunate, but currently, animal testing is unavoidable for new medicinal products. Hopefully future scientific developments will not require the employment of animal testing to ensure the safety of new pharmaceuticals.
I agree so much with your post Dysmorphia!
- I also do my best to make sure to buy food where I think the animals were treated good.
I love animals, I care about them...... I can cry when I see an animal suffer!
Originally Posted by MixMastahTee
It's an important topic for all living creatures.
I work with animals,and also volunteer at my animal shelter,and have for 14 years. But I also eat meat,wear leather and own fur. If it is to save people,fine. But not for cosmetics or such things-thats why I only shop at the body shop and similar places
This is not something that bothers me and it's not something I ever really think about, I don't have an issue with animal testing. Especially when it comes to Medicine.
I'm glad my diabetic uncle is still alive thanks to animal testing.
I propose we replace animal testing with Inmate testing. These tests serve a valuable purpose, and we do happen to have an overcrowded prison system. Test dangerous chemicals and and cosmetics on death row. I'm sure we already do, but really it should become standard.
Or we could not do that and just stop locking up people for drug related charges. I'd rather not test dangerous chemicals and crap on people who were thrown in a cell due to the "War on Drugs". I suppose that's for a completely different thread though.
Originally Posted by iggy